The developing material is grafted into defects in order to recover the anatomy and function of the damaged structures as soon as possible, in order to improve the quality of life of the patient.
Diseño de nuevos materiales sintéticos con una forma particular para mejorar la regeneración ósea.
Optimize biomechanical properties
To evaluate and characterize the biocompatibility of the particle in vitro, evaluating mainly the toxicology of the optimized particle and its interaction with cells in culture.
Fabricate the optimized prototype under GMP conditions and evaluate its efficacy and safety in vivo. For them it will be necessary to manufacture a pilot lot to determine the osteoinductive and osteoconductive properties of the bioparticles in the medium animal model.
Analyze the results obtained and define the preliminary optimization strategy for manufacturing on an industrial scale